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ICA-27243
Artikelnummer: TGM-T15545-100mg
Description: ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 µM). ICA-27243 also has antiepileptic and anticonvulsant effects. Target: Potassium Channel. Smiles: Fc1ccc(cc1F)C(=O)Nc1ccc(Cl)nc1. References: Wickenden...
| Anwendung: | Kv7.2/Kv7.3 subunit-containing channels activator |
| CAS | 325457-89-4 |
| MW: | 268.65 D |
ab 37,00 €
ICA 27243
Artikelnummer: Cay40827-10
ICA 27243 is an activator of heteromeric voltage-gated potassium channels containing Kv7.2 and Kv7.3 subunits (Kv7.2/Kv7.3). It enhances rubidium efflux in an agonist-induced rubidium efflux assay using CHO cells expressing Kv7.2/Kv7.3 channels (EC50 = 0.38 µM). ICA 27243 is selective for heteromeric Kv7.2/Kv7.3...
| Schlagworte: | ICA 027243, N-(6-chloro-3-pyridinyl)-3,4-difluoro-benzamide |
| Anwendung: | Kv7.2/Kv7.3 subunit-containing channels activator |
| CAS | 325457-89-4 |
| MW: | 268.7 D |
ab 133,00 €
