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CCT020312
Artikelnummer: TGM-T14902-100mg
Description: CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A. Target: PERK. Smiles: CCN(CC)CCC(=O)N1N=C(CC1c1ccc(Br)cc1)c1c(-c2ccccc2)c2cc(Br)ccc2[nH]c1=O. References: Stockwell SR, et al.Mechanism-based screen for G1/S...
| Anwendung: | EIF2AK3 activator |
| CAS | 324759-76-4 |
| MW: | 650.4 D |
ab 57,00 €
CCT020312
Artikelnummer: Cay36577-1
CCT020312 is an activator of eukaryotic translation initiation factor 2alpha kinase 3 (EIF2AK3). It increases phosphorylation of eIF2alpha at serine 51 in HT-29 colon carcinoma and MCF-7 breast cancer cells when used at a concentration of 10 µM, an effect not seen in cells transfected with EIF2AK3 siRNA. It reduces...
| Schlagworte: | 6-bromo-3-[5-(4-bromophenyl)-1-[3-(diethylamino)-1-oxopropyl]-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-2(1H)-quinolinone |
| Anwendung: | EIF2AK3 activator |
| CAS | 324759-76-4 |
| MW: | 650.4 D |
ab 55,00 €
