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BTSA1
Artikelnummer: TGM-T5104-100mg
Description: BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. Target: Apoptosis, BCL. Smiles: O=C1N(N=C(\C1=N/Nc1nccs1)c1ccccc1)c1nc(cs1)-c1ccccc1. References: Reyna DE, et al. Direct...
| Anwendung: | Bax activator |
| CAS | 314761-14-3 |
| MW: | 430.51 D |
ab 40,00 €
BTSA1
Artikelnummer: Cay37305-10
BTSA1 is an activator of Bax. It binds to the Bax N-terminal activation site, also known as the trigger site (IC50 = 250 nM), and induces Bax translocation membrane permeabilization in liposomes when used at concentrations ranging from 100 to 400 nM. BTSA1 (0.1-1 µM) induces apoptosis in various human and mouse...
| Schlagworte: | Bax Trigger Site Activator 1, 3-phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione, 4-[2-(2-thiazolyl)hydrazone] |
| Anwendung: | Bax activator |
| CAS | 314761-14-3 |
| MW: | 430.5 D |
ab 111,00 €
