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Etravirine
Artikelnummer: Cay20946-10
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is active against the wild-type HIV-1 strains LAI, SF2, and Ba-L (EC50s = 1.4-4.8 nM) but not the HIV-2 strain ROD (EC50 = 3,479 nM). Etravirine is also active against 18 HIV-1 strains carrrying NNRTI resistance-associated mutations (EC50s =...
| Schlagworte: | R165335, TMC125, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile |
| Anwendung: | Reverse transcriptase inhibitor, NNRTI |
| CAS | 269055-15-4 |
| MW: | 435.3 D |
ab 94,00 €
Etravirine
Artikelnummer: TGM-T2551-100mg
Description: Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in...
| Schlagworte: | TMC125, R165335 |
| Anwendung: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 269055-15-4 |
| MW: | 435.28 D |
ab 42,00 €
