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Glucosylceramide synthase-IN-1
Artikelnummer: TGM-T62898-25mg
Description: Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor, acting on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM), and can be used to study Gaucher disease. Target: Others. Smiles:...
| Anwendung: | UDP-glucose ceramide glucosyltransferase (UGCG) inhibitor |
| CAS | 2601393-20-6 |
| MW: | 460.42 D |
ab 1.270,00 €
TP-060
Artikelnummer: Cay41127-1
TP-060 is an inhibitor of UDP-glucose ceramide glucosyltransferase (IC50 = 0.031 µM). It is selective for UDP-glucose ceramide glucosyltransferase over human ether-a-go-go (hERG) at 10 µM but also inhibits serotonin receptors (5-HT, IC50 = 0.31 µM). In vivo, TP-060 (30 mg/kg per day) decreases the cerebral cortex...
| Schlagworte: | T-036,... |
| Anwendung: | UDP-glucose ceramide glucosyltransferase (UGCG) inhibitor |
| CAS | 2601393-20-6 |
| MW: | 460.4 D |
ab 136,00 €
