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SGC6870
Artikelnummer: TGM-T69580-25mg
Description: SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases. Target: Others. Smiles: C(=O)(N1[C@@H](C=2C(NC(=O)C1)=CC=C(C)C2)C3=CC(C)=CC(C)=C3)C=4SC(Br)=CC4
| Anwendung: | PRMT6 inhibitor |
| CAS | 2561471-27-8 |
| MW: | 469.39 D |
ab 547,00 €
SGC6870
Artikelnummer: Cay33712-1
SGC6870 is an inhibitor of protein arginine methyltransferase 6 (PRMT6, IC50 = 77 nM). It is selective for PRMT6 over a panel of 76 methyltransferases, G protein-coupled receptors (GPCRs), ion channels, receptors, and other enzymes at 1 µM. SGC6870 decreases the levels of dimethylated arginine 2 on histone 3...
| Schlagworte: | 4-[(5R-bromo-2-thienyl)carbonyl]-5-(3,5-dimethylphenyl)-1,3,4,5-tetrahydro-7-methyl-2H-1,4-benzodiazepin-2-one |
| Anwendung: | PRMT6 inhibitor |
| CAS | 2561471-27-8 |
| MW: | 469.4 D |
ab 81,00 €
