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NVS-PAK1-C
Artikelnummer: TGM-T35928-1mg
Description: NVS-PAK1-1 is a potent allosteric inhibitor of PAK1 with an IC 50 of 5 nM for dephosphorylated PAK1 and 6 nM for phosphorylated PAK1 as assessed. Inhibition is ATP-competitive, most likely due to indirect competition due to incompatibility of ATP binding with the DFG-out binding conformation of the...
| Schlagworte: | NVS-PAK1-C |
| Anwendung: | Negative control |
| CAS | 2250019-95-3 |
| MW: | 465.9 D |
77,00 €
NVS-PAK1-C
Artikelnummer: Cay19965-1
NVS-PAK1-C is a negative control for the allosteric PAK1 inhibitor NVS-PAK1-1 (Cay-19964). See the Structural Genomic Consortium (SGC) website for more information.Formal Name: (3S)-(3-[[2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl]amino]-N,N-dimethyl-1-pyrrolidinecarboxamide. CAS...
| Schlagworte: | (S)-3-((2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N,N-dimethylpyrrolidine-1-carbox... |
| Anwendung: | Negative control |
| CAS | 2250019-95-3 |
| MW: | 465.9 D |
ab 44,00 €
