Zu "219989-84-1" wurden 2 Artikel gefunden!
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Ixabepilone
Artikelnummer: TGM-T6864-1mg
Description: Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. Target: Apoptosis, Microtubule Associated....
| Schlagworte: | BMS 247550-1, Azaepothilone B, Ixempra, BMS 247550 |
| Anwendung: | Targets tubulin beta (TUBB) |
| CAS | 219989-84-1 |
| MW: | 506.7 D |
ab 52,00 €
Ixabepilone
Artikelnummer: Cay23732-10
Ixabepilone is an epothilone with broad-spectrum anticancer activity against a panel of 21 cancer cell lines (IC50s = 1.4-34.5 nM). It stabilizes and induces the polymerization of microtubules and induces cell cycle arrest during mitosis. Ixabepilone is cytotoxic to HCT116/VM46 and A2780Tax clonogenic cells, which...
| Schlagworte: | Azaepothilone B, BMS-247550,... |
| Anwendung: | Antineoplastic, antimitotic, Tubulin depolymerization inhibitor |
| CAS | 219989-84-1 |
| MW: | 506.7 D |
ab 132,00 €
