Zu "2089389-15-9" wurden 2 Artikel gefunden!
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(R)-ZINC3573
Artikelnummer: Cay41312-10
(R)-ZINC3573 is an agonist of MAS-related G protein-coupled receptor family member X2 (MRGPRX2). It induces beta-arrestin recruitment in a reporter assay using MRGPRX2-expressing HTLA cells and calcium mobilization in LAD 2 mast cells (EC50s = 0.74 and 1 µM, respectively). (R)-ZINC3573 is selective for MRGPRX2 over...
| Schlagworte: | (R)-ZINC72453573, N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3R-pyrrolidinamine |
| Anwendung: | MRGPRX2 agonist |
| CAS | 2089389-15-9 |
| MW: | 307.4 D |
ab 107,00 €
(R)-ZINC-3573
Artikelnummer: TGM-T29221-100mg
Description: (R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release. Target: MRGPR. Smiles: CN(C)[C@@H]1CCN(C1)c1cc(nc2ccnn12)-c1ccccc1. References: Lansu K, et al. In silico design of novel probes for the...
| Schlagworte: | ZINC 3573 |
| CAS | 2089389-15-9 |
| MW: | 307.39 D |
ab 40,00 €
