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ML241 hydrochloride
Artikelnummer: TGM-T4684-100mg
Description: ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97...
| Anwendung: | Selective ATPase p97 inhibitor |
| CAS | 2070015-13-1 |
| MW: | 408.92 D |
ab 46,00 €
ML-241 (hydrochloride)
Artikelnummer: Cay40400-10
ML-241 is an ATP-competitive inhibitor of the ATPase p97 (IC50 = 0.11 µM) that is selective for the D2 domain of p97. It disrupts the endoplasmic reticulum-associated degradation (ERAD) pathway, preventing the degradation of p97-dependent proteasome substrates in a reporter assay using HeLa cells (IC50 = 3.5 µM) and...
| Schlagworte: | 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-4-quinazolinamine, monohydrochloride |
| Anwendung: | Selective ATPase p97 inhibitor |
| CAS | 2070015-13-1 |
| MW: | 408.9 D |
ab 67,00 €
