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Rucaparib monocamsylate
Artikelnummer: TGM-T16807-100mg
Description: Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains. Target: PARP. Smiles: [H][C@@]12CC[C@@](CS(O)(=O)=O)(C(=O)C1)C2(C)C.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23. References: Thomas HD,...
| Schlagworte: | Rucaparib Camsylate |
| Anwendung: | Targets poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] (PARP1) |
| CAS | 1859053-21-6 |
| MW: | 555.66 D |
ab 55,00 €
Rucaparib (camsylate)
Artikelnummer: Cay40218-100
Rucaparib is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor. It reduces PARP1 activity in D283 Med medulloblastoma cells by 91.7% when used at a concentration of 1 µM. Rucaparib selectively inhibits the proliferation of MDA-MB-436 breast cancer cells expressing mutant BRCA1 (IC50s = 1.3 µM) over MCF-7 breast...
| Schlagworte: | AG-014699, PF-01367338, (1S,4R)-7,7-dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic acid, compd. with... |
| Anwendung: | PARP1 inhibitor |
| CAS | 1859053-21-6 |
| MW: | 555.7 D |
ab 81,00 €
