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YM-53601
Artikelnummer: Cay18113-500
YM-53601 is a squalene synthase inhibitor (IC50s = 79 and 90 nM in HepG2 cells and rat liver microsomes, respectively). It inhibits cholesterol biosynthesis in rats (ED50 = 32 mg/kg). YM-53601 dose-dependently reduces plasma triglyceride and non-HDL cholesterol levels in hamsters fed both normal and high-fat diets....
| Schlagworte: | 2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole, monohydrochloride |
| Anwendung: | Squalene synthase inhibitor |
| CAS | 182959-33-7 |
| MW: | 372.9 D |
ab 295,00 €
YM-53601
Artikelnummer: TGM-T26345-1mg
Description: YM-53601 is a potent squalene synthase (SQS) inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits farnesyl diphosphate farnesyltransferase 1 (FDFT1).YM-53601 exhibits potential antiviral activity and enhances...
| Schlagworte: | YM53601 , YM 53601 |
| Anwendung: | Squalene synthase inhibitor |
| CAS | 182959-33-7 |
| MW: | 372.86 D |
ab 153,00 €
