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BMS-8
Artikelnummer: TGM-T26859-100mg
Description: BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 µM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers. Target: PD-1/PD-L1. Smiles: Cc1c(COc2ccc(CN3CCCCC3C(O)=O)cc2Br)cccc1-c1ccccc1. References: Gaudy-Marqueste C, Dussouil AS, Carron R, Troin L, Malissen N,...
| CAS | 1675201-90-7 |
| MW: | 494.42 D |
ab 34,00 €
BMS-8
Artikelnummer: Cay22355-1
BMS-8 is a small molecule inhibitor of the protein-protein interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.Formal Name:...
| Schlagworte: | 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-2-piperidinecarboxylic acid |
| Anwendung: | PD-1/PD-L1 interaction inhibitor, PD-L1 dimerization inhibitor |
| CAS | 1675201-90-7 |
| MW: | 494.4 D |
ab 36,00 €
