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XY1
Artikelnummer: TGM-T7157-100mg
Description: XY1 is a close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), intended as a negative control for SGC707 in studies involving PRMT3 action. Target: Histone Methyltransferase. Smiles: O=C(CNC(=O)Nc1ccc2ccccc2c1)N1CCCC1. References: Børsting C, Tomas C,...
| Anwendung: | PRMT3 inhibitor negative control |
| CAS | 1624117-53-8 |
| MW: | 297.35 D |
ab 31,00 €
XY1
Artikelnummer: Cay17518-5
Protein arginine N-methyltransferase 3 (PRMT3, Cay-11642) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 (Cay-17017) is a potent, selective allosteric inhibitor of PRMT3 (IC50 = 50 nM). It inhibits the methylation of histones in cells with an IC50 value below 1 µM. XY1 is a close...
| Schlagworte: | N-2-naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea |
| Anwendung: | PRMT3 inhibitor negative control |
| CAS | 1624117-53-8 |
| MW: | 297.4 D |
ab 145,00 €
