Zu "1561178-17-3" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
SGC0946
Artikelnummer: TGM-T3082-10mg
Description: SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM), selectively kill mixed lineage leukemia cells. Target: Histone Methyltransferase. Smiles: CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12. References: Yu W, et al. Nat...
| Anwendung: | Potent DOT1L inhibitor |
| CAS | 1561178-17-3 |
| MW: | 618.57 D |
ab 42,00 €
SGC0946
Artikelnummer: Cay13967-10
DOT1L is a protein methyltransferase (PMT). It is the only enzyme known to methylate histone 3 at lysine 79 (H3K79), where it catalyzes mono-, di-, and trimethylation. Proper DOT1L function is necessary for transcriptional activation of many genes, DNA damage repair, and cell cycle regulation. SGC0946 is a potent...
| Schlagworte: | 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofura... |
| Anwendung: | Potent DOT1L inhibitor |
| CAS | 1561178-17-3 |
| MW: | 618.6 D |
ab 132,00 €
