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TC-S 7009
Artikelnummer: TGM-T17009-100mg
Description: TC-S 7009 is a potent and selective HIF-2alpha inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2alpha than HIF-1alpha (Kd >> 5µM). TC-S 7009 disrupts HIF-2alpha heterodimerization, reduces HIF-2alpha target gene expression, and diminishes DNA binding activity. Target: HIF. Smiles:...
| Anwendung: | EPAS-1 PAS-B domain heterodimerization inhibitor |
| CAS | 1422955-31-4 |
| MW: | 308.65 D |
ab 63,00 €
HIF-2alpha Antagonist 2
Artikelnummer: Cay16971-5
HIF-2alpha antagonist 2 is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha) PAS-B domain heterodimerization. It binds to the HIF-2alpha PAS-B domain (Kd = 81 nM) to inhibit heterodimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT) PAS-B domain in cell-free assays when used at...
| Schlagworte: | N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine |
| Anwendung: | EPAS-1 PAS-B domain heterodimerization inhibitor |
| CAS | 1422955-31-4 |
| MW: | 308.7 D |
ab 53,00 €
