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BRD4770
Artikelnummer: TGM-T1923-100mg
Description: BRD4770, a histone methyltransferase G9a inhibitor, induces cell senescence. Target: Histone Methyltransferase. Smiles: COC(=O)c1ccc2n(CCCc3ccccc3)c(NC(=O)c3ccccc3)nc2c1. References: Yuan Y, et al. ACS Chem Biol. 2012, 7(7), 1152-1157.
| Anwendung: | EHMT2 inhibitor |
| CAS | 1374601-40-7 |
| MW: | 413.47 D |
ab 31,00 €
BRD4770
Artikelnummer: Cay11787-1
BRD4770 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, decreasing di- and trimethylation on lysine 9 of histone 3 (EC50 = 5 µM). Through its effects on EHMT2, BRD4770 induces senescence in the pancreatic cancer cell line PANC-1 without initiating apoptosis. It also blocks both...
| Schlagworte: | HMTase Inhibitor VI, 2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid, methyl ester |
| Anwendung: | EHMT2 inhibitor |
| CAS | 1374601-40-7 |
| MW: | 413.5 D |
ab 44,00 €
