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BMS-5
BMS-5

Artikelnummer: SYN-1024-M001

Soluble in DMSO. Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has...
Schlagworte: BMS5
Anwendung: LIMK1 / LIMK2 inhibitor
CAS 1338247-35-0
MW: 431,3 D
ab 106,00 €
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BMS-5
BMS-5

Artikelnummer: Cay21072-1

BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively. LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin. This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho...
Schlagworte: LIM Kinase Inhibitor I, LIMKi 3,...
Anwendung: LIMK1 / LIMK2 inhibitor
CAS 1338247-35-0
MW: 431.3 D
ab 65,00 €
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