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AG 555
AG 555

Artikelnummer: TGM-T4326-100mg

Description: AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor. Target: EGFR, Reverse Transcriptase. Smiles: Oc1ccc(C=C(C#N)C(=O)NCCCc2ccccc2)cc1O. References: Michaelis M, et al. Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive...
Schlagworte: Tyrphostin B46, Tyrphostin AG 555
Anwendung: EGFR inhibitor
CAS 133550-34-2
MW: 322.36 D
ab 40,00 €
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AG-555
AG-555

Artikelnummer: Cay23247-10

AG-555 is a tyrphostin inhibitor of the EGF receptor (EGFR, IC50 = 0.7 µM). It selectively inhibits EFGR over ErbB2 (IC50 = 35 µM). AG-555 inhibits EGF-dependent growth of HER 14 cells (IC50 = 2.5 µM) as well as the growth of psoriatic keratinocytes isolated from patients with psoriasis when used at concentrations...
Schlagworte: Tyrphostin AG-555, Tyrphostin B46, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide
Anwendung: EGFR inhibitor
CAS 133550-34-2
MW: 322.4 D
ab 66,00 €
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