Zu "1270084-92-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
APX-115 free base
Artikelnummer: TGM-T10353-100mg
Description: APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 µM, 0.57 µM, and 0.63 µM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury. Target: NADPH-oxidase, NADPH. Smiles:...
| Schlagworte: | Ewha-18278 free base |
| CAS | 1270084-92-8 |
| MW: | 279.34 D |
ab 52,00 €
APX-115
Artikelnummer: Cay41110-1
APX-115 is an inhibitor of NADPH oxidase 1 (NOX1), NOX2, and NOX4 (Kis = 1.08, 0.57, and 0.63 µM, respectively, for the human enzymes). It is selective for these enzymes over xanthine oxidase and glucose oxidase (Kis = >100 µM for both). APX-115 (10 or 20 µM) prevents RANKL-induced increases in reactive oxygen...
| Schlagworte: | EWHA-18278, 3-phenyl-4-propyl-1-(2-pyridinyl)-1H-pyrazol-5-ol |
| Anwendung: | NOX1 / NOX2 / NOX4 inhibitor |
| CAS | 1270084-92-8 |
| MW: | 279.3 D |
ab 35,00 €
