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KHS 101
Artikelnummer: TGM-T4968-100mg
Description: KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation. Target: Microtubule Associated. Smiles: C(NC=1N=C(NCC(C)C)C=CN1)C=2N=C(SC2)C3=CC=CC=C3. References: Wurdak H, et al. A small molecule accelerates neuronal...
| Anwendung: | Neuronal differentiation inducer, Hsp60 inhibitor |
| CAS | 1262770-73-9 |
| MW: | 339.46 D |
ab 45,00 €
KHS-101
Artikelnummer: Cay37544-10
KHS-101 is an inhibitor of heat shock protein 60 (Hsp60), also known as HSPD1, and an inducer of neuronal differentiation. It inhibits the refolding activity of the complex of Hsp60 with the co-chaperone Hsp10, also known as HSPE1, in a cell-free assay (IC50 = 14.4 µM) and induces autophagy in GBM1 glioblastoma...
| Schlagworte: | N4-(2-methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediamine |
| Anwendung: | Neuronal differentiation inducer, Hsp60 inhibitor |
| CAS | 1262770-73-9 |
| MW: | 339.5 D |
ab 107,00 €
