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MLN0905
MLN0905

Artikelnummer: TGM-T2704-10mg

Description: MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM). Target: PLK. Smiles: CN(C)CCCc1cnc(C)c(Nc2ncc3CC(=S)Nc4cc(ccc4-c3n2)C(F)(F)F)c1. References: Duffey MO, et al. J Med Chem, 2012, 55(1), 197-208.
Schlagworte: PLK1 Inhibitor
Anwendung: Plk1 inhibitor
CAS 1228960-69-7
MW: 486.56 D
ab 55,00 €
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MLN0905
MLN0905

Artikelnummer: Cay31115-1

MLN0905 is an inhibitor of polo-like kinase 1 (Plk1, IC50 = 2 nM). It inhibits 95% of Plk1 activity but also inhibits the activity of 10 additional kinases by greater than or equal to 90% in a panel of 359 kinases at 1 µM. MLN0905 reduces phosphorylation of histone H3 at serine 10 (H3S10Ph), a marker of cell cycle...
Schlagworte: 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)-6H-pyrimido[5,4-d][1]benzazepi...
Anwendung: Plk1 inhibitor
CAS 1228960-69-7
MW: 486.6 D
ab 69,00 €
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