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Nelarabine
Artikelnummer: TGM-T6603-100mg
Description: Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 µM in tumor cells. Target: Apoptosis, DNA/RNA Synthesis, Nucleoside Antimetabolite/Analog. Smiles: COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O. References: Beesley AH, et al. Br J...
| Schlagworte: | GW 506U78, 506U78, Nelzarabine |
| Anwendung: | Antineoplastic, Antimetabolite |
| CAS | 121032-29-9 |
| MW: | 297.27 D |
ab 37,00 €
Nelarabine
Artikelnummer: Cay20248-1
Nelarabine is a purine nucleoside analog that is used as a cytotoxic agent in hematological malignancies. Nelarabine is converted into arabinosyl-guanine (ara-G) in the blood, and ara-G is selectively accumulated in T cells and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and...
| Schlagworte: | GW 506U78, Nelzarabine, 9-beta-D-arabinofuranosyl-6-methoxy-9H-purin-2-amine |
| Anwendung: | Antineoplastic |
| CAS | 121032-29-9 |
| MW: | 297.3 D |
ab 52,00 €
Nelarabine
Artikelnummer: LKT-N1744.10
A chemotherapy drug used in T-cell acute lymphoblastic leukemia. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive...
| Schlagworte: | 506U78, (2R,3S,4R,5R)-2-(2-amino-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| Anwendung: | Purine nucleoside analog |
| CAS | 121032-29-9 |
| MW: | 297,26 D |
ab 104,00 €
