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Telotristat Etiprate
Telotristat Etiprate

Artikelnummer: TGM-T6044-100mg

Description: Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Target: Hydroxylase. Smiles: OC(=O)CNC(=O)c1ccccc1.CCOC(=O)[C@@H](N)Cc1ccc(cc1)-c1cc(O[C@H](c2ccc(Cl)cc2-n2ccc(C)n2)C(F)(F)F)nc(N)n1. References: Pappas C,...
Schlagworte: LX 1606 Hippurate, LX1606 (Hippurate)
Anwendung: Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2)
CAS 1137608-69-5
MW: 754.15 D
ab 40,00 €
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Telotristat Etiprate
Telotristat Etiprate

Artikelnummer: Cay25342-5

Telotristat etiprate is a prodrug form of telotristat, which is an inhibitor of tryptophan hydroxylase 1 (TPH1). Telotristat etiprate (15-300 mg/kg) reduces levels of serotonin (5-HT, Cay-14332) in mouse jejunum and blood but not brain. It inhibits increases in IL-1beta and IL-6 levels, histological damage in the...
Schlagworte: LX 1032 hippurate, LX 1606 hippurate,...
Anwendung: TPH1 inhibitor prodrug
CAS 1137608-69-5
MW: 754.2 D
ab 128,00 €
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