Zu "1092776-63-0" wurden 2 Artikel gefunden!
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IT1t dihydrochloride
Artikelnummer: TGM-T11693L-100mg
Description: IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4. Target: CXCR. Smiles: Cl.Cl.CC1(C)CN2C(CS\C(NC3CCCCC3)=N/C3CCCCC3)=CSC2=N1. References: Van Hout A, et al. Comparison of cell-based assays for the identification and evaluation of...
| CAS | 1092776-63-0 |
| MW: | 479.57 D |
ab 37,00 €
IT1t (hydrochloride)
Artikelnummer: Cay28434-10
IT1t is a chemokine (C-X-C motif) receptor 4 (CXCR4) antagonist (IC50s = 8 and 11 nM for the human and rat receptors, respectively). It is selective for CXCR4 over human ether-a-go-go-related gene potassium channels (hERG/Kv11.1, IC50 = 13,240 nM). IT1t inhibits calcium mobilization induced by chemokine...
| Schlagworte: | N,N'-dicyclohexyl-carbamimidothioic acid, (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester, dihydrochloride |
| Anwendung: | CXCR4 antagonist |
| CAS | 1092776-63-0 |
| MW: | 479.6 D |
ab 150,00 €
