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Debio 0932
Artikelnummer: TGM-T15088-2mg
Description: Debio 0932 is an orally active inhibitor of HSP90 (IC50s: 100 and 103 nM for HSP90alpha and HSP90beta, respectively). Target: HSP. Smiles: CN(C)c1cc2OCOc2cc1Sc1nc2c(N)nccc2n1CCNCC(C)(C)C. References: Bao R, et al. CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for...
| Schlagworte: | CUDC-305 |
| Anwendung: | Hsp90 inhibitor |
| CAS | 1061318-81-7 |
| MW: | 442.58 D |
63,00 €
CUDC-305
Artikelnummer: Cay24683-1
CUDC-305 is an orally bioavailable inhibitor of heat shock protein 90 (Hsp90, Cay-22734, Cay-22735). It binds to Hsp90alpha and Hsp90beta (IC50s = 100 and 103 nM for purified protein, respectively) as well as Hsp90 isolated from non-small cell lung cancer (NSCLC) cells resistant to erlotinib (Cay-10483, IC50 = 70...
| Schlagworte: | 4-amino-2-[[6-(dimethylamino)-1,3-benzodioxol-5-yl]thio]-N-(2,2-dimethylpropyl)-1H-imidazo[4,5-c]pyridine-1-ethanamine |
| Anwendung: | Hsp90 inhibitor |
| CAS | 1061318-81-7 |
| MW: | 442.6 D |
ab 78,00 €
