Zu "1041852-85-0" wurden 2 Artikel gefunden!
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AZD7507
Artikelnummer: TGM-T14380-100mg
Description: AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity. Target: HER, CSF-1R, Sodium Channel. Smiles: COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CCN(CCO)CC1. References: Scott DA, et al. Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the...
| Anwendung: | FMS inhibitor |
| CAS | 1041852-85-0 |
| MW: | 454.5 D |
ab 48,00 €
AZD 7507
Artikelnummer: Cay37485-1
AZD 7507 is an inhibitor of CSF-1 receptor tyrosine kinase (FMS, IC50 = 3 nM). It is selective for FMS over c-KIT, aurora kinase 5 (ARK-5), FMS-related tyrosine kinase 4 (FLT4), p90 ribosomal S6 kinase (RSK1), and 77 other kinases at 1 µM. AZD 7505 (100 nM) induces apoptosis in isolated Fms+ mouse bone marrow cells...
| Schlagworte: | 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)-1-piperazinyl]-7-methoxy-3-cinnolinecarboxamide |
| Anwendung: | FMS inhibitor |
| CAS | 1041852-85-0 |
| MW: | 454.5 D |
ab 55,00 €
