Zu "(base)" wurden 1688 Artikel gefunden!
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AZD-9056 free base
Artikelnummer: TGM-T30267-100mg
Description: AZD9056 is a potent, selective, orally bioavailable P2X7 receptor antagonist. Target: Others. Smiles: OCCCNCCCc1ccc(Cl)c(c1)C(=O)NCC12CC3CC(CC(C3)C1)C2. References: Eser A, Colombel JF, Rutgeerts P, Vermeire S, Vogelsang H, Braddock M, Persson T, Reinisch W. Safety and Efficacy of an Oral Inhibitor of...
| Schlagworte: | AZD-9056, AZD9056, AZD 9056 |
| CAS | 345304-65-6 |
| MW: | 419 D |
ab 1.520,00 €
Sudoterb free base
Artikelnummer: TGM-T3480-10mg
Description: Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate. Target: ATPase. Smiles: N(C(=O)C=1C=CN=CC1)N2C(=CC(CN3CCN(CC3)C4=CC(C(F)(F)F)=CC=C4)=C2C)C5=CC=CC=C5. References: Didilescu C, Craiova UM. [Present and future in the use of anti-tubercular drugs]. Pneumologia....
| Schlagworte: | Sudoterb |
| CAS | 676266-31-2 |
| MW: | 519.56 D |
ab 40,00 €
U-34728E free base
Artikelnummer: TGM-T34978-500mg
Description: U-34728E free base is a bioactive chemical. Target: Others. Smiles: CCCC1CC(N(CCO)C1)C(=O)NC(C(C)Cl)C1OC(SC)C(O)C(O)C1O. References: Zheng M, He C, He Q. Fate of free chlorine in drinking water during distribution in premise plumbing. Ecotoxicology. 2015 Dec,24(10):2151-5. doi:...
| Schlagworte: | U34728E free base, U-34728E |
| CAS | 40984-87-0 |
| MW: | 455.01 D |
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ORY-1001 free base
Artikelnummer: TGM-T28269-100mg
Description: ORY-1001 is a KDM1A inhibitor (IC50 100uM, SMOX 7uM). Treatment of THP-1 (MLL-AF9) cells with ORY-1001, results in a time/dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers (EC50 me2H3K4 and FACS CD11b <1nM). ORY-1001 induces apoptosis in...
| Schlagworte: | RG6016, RG-6016, ORY1001, ORY 1001, RG 6016, ORY-1001 |
| CAS | 1431304-21-0 |
| MW: | 230.35 D |
ab 1.520,00 €
RPC425 free base
Artikelnummer: TGM-T28614-100mg
Description: RPC425 is a noncompetitive inhibitors of the Betaine-gamma-Aminobutyric Acid Transporter 1 (BGT1). Target: Others. Smiles: C(=CCCN(C)C1C(C(O)=O)=CCCC1)(C2=C(C)C=CS2)C3=C(C)C=CS3. References: (16) Vogensen, S. B., Jørgensen, L., Madsen, K. K., Borkar, N., Wellendorph, P., Skovgaard-Petersen, J.,...
| Schlagworte: | RPC 425, RPC-425, RPC425 |
| CAS | 1426208-69-6 |
| MW: | 401.59 D |
ab 2.121,00 €
S-8510 free base
Artikelnummer: TGM-T28653-100mg
Description: S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ameliorated memory impairment induced by cholinergic deficit in the water maze paradigm...
| Schlagworte: | S8510, SB-737552, SB737552, SB 737552, S-8510, S 8510 |
| CAS | 151224-83-8 |
| MW: | 242.23 D |
ab 2.272,00 €
SRA880 free base
Artikelnummer: TGM-T28851-500mg
Description: SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding affinity to the human dopamine D4 receptors. SRA880 positively modulates release of...
| Schlagworte: | SRA 880, NVP SRA880, NVPSRA880, SRA880, SRA-880, NVP-SRA880 |
| CAS | 187218-90-2 |
| MW: | 464.56 D |
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XC-302 free base
Artikelnummer: TGM-T29165-100mg
Description: XC-302 is a multi-targeted inhibitor, it induces autophagy of nasopharyngeal cancer cells via inhibiting the PI3K/AKT/mTOR signaling pathway. Target: Others. Smiles: N(C1=C2C(=NC(NC3=CC4=C(C=C3)N=CC=C4)=N1)N=CN2)C5CC5. References: Wang KF, Yang H, Jiang WQ, Li S, Cai YC. Puquitinib mesylate (XC-302)...
| Schlagworte: | XC302, XC-302, Puquitinib, XC 302 |
| CAS | 916890-10-3 |
| MW: | 317.35 D |
ab 1.520,00 €
DBO-83 free base
Artikelnummer: TGM-T31220-25mg
Description: DBO-83 free base is the free base form of DBO-83. DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities. Target: Others. Smiles: ClC1=NN=C(C=C1)N2CC3NC(C2)CC3. References: Decker MW, Meyer MD, Sullivan JP. The therapeutic potential of nicotinic...
| Schlagworte: | DBO 83 free base |
| CAS | 286946-32-5 |
| MW: | 224.69 D |
1.520,00 €
AUY-954 free base
Artikelnummer: TGM-T30215-1mg
Description: AUY-954 is an effective selective S1P(1) modulator. It can significantly reduce the local expression of EAN rat sciatic nerve T cells, B cells, macrophage infiltration, inflammatory demyelination, interleukin-17 and matrix metalloproteinase-9. Target: Others. Smiles:...
| Schlagworte: | NVP-AUY954, AUY 954, AUY-954, AUY954 |
| CAS | 820240-77-5 |
| MW: | 455.49 D |
ab 170,00 €
Bicisate (Free base)
Artikelnummer: TGM-T30444L-25mg
Description: Bicisate is usually complex with technetium Tc99m for its usage as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). Target: Others. Smiles: [C@H](C(OCC)=O)(NCCN[C@H](C(OCC)=O)CS)CS. References: Chao MY, Liu KT, Hsia YC, Liao MH, Shen LH. Direct...
| Schlagworte: | Bicisate |
| CAS | 121251-02-3 |
| MW: | 324.46 D |
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LY-53857 free base
Artikelnummer: TGM-T33018-500mg
Description: LY-53857 free base is a bioactive chemical. Target: Others. Smiles: [H][C@@]12Cc3cn(C(C)C)c4cccc(c34)[C@@]1([H])C[C@H](CN2C)C(=O)OC(C)C(C)O. References: Inoue-Matsuhisa E, Sogo S, Mizota A, Taniai M, Takenaka H, Mano T. Effect of MCI-9042, a 5-HT2 receptor antagonist, on retinal ganglion cell death and...
| CAS | 32896-53-0 |
| MW: | 384.52 D |
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