Zu "(base)" wurden 1688 Artikel gefunden!
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ITI-214 free base
Artikelnummer: TGM-T11688-100mg
Description: ITI-214 free base, a picomolar PDE1 inhibitor (Ki = 58 pM), exhibits excellent selectivity against other PDE family members and a range of enzymes, receptors, transporters, and ion channels. Target: Others. Smiles: [H][C@@]12CCC[C@]1([H])N1C(=N2)N(C)C(=O)c2c(Nc3ccccc3)n(Cc3ccc(cc3)-c3cccc(F)n3)nc12....
| Schlagworte: | ITI214 free base |
| CAS | 1160521-50-5 |
| MW: | 507.56 D |
ab 787,00 €
LIT-001 free base
Artikelnummer: TGM-T11856-500mg
Description: LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM, Ki=226 nM). Target: Others. Smiles: C(=O)(N1C=2C(NC3=C(C1)C=NN3C)=CC=CC2)C4=CC(C)=C(CNC(=O)N5[C@H](C(N(C)C)=S)CCC5)C=C4. References: Frantz...
| CAS | 2245072-20-0 |
| MW: | 531.67 D |
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AFP464 free base
Artikelnummer: TGM-T10258-100mg
Description: AFP464 (NSC710464) free base is an active HIF-1alpha inhibitor (IC50: 0.25 µM) and a potent aryl hydrocarbon receptor (AhR) activator. Target: HIF. Smiles: FC1=C2C(C(=O)C=C(O2)C3=CC(F)=C(NC([C@H](CCCCN)N)=O)C=C3)=C(N)C(F)=C1C. References: Terzuoli E1, Aminoflavone, a ligand of the aryl hydrocarbon...
| Schlagworte: | NSC710464 free base |
| CAS | 468719-52-0 |
| MW: | 448.44 D |
ab 2.421,00 €
APX-115 free base
Artikelnummer: TGM-T10353-10mg
Description: APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 µM, 0.57 µM, and 0.63 µM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury. Target: NADPH-oxidase, NADPH. Smiles:...
| Schlagworte: | Ewha-18278 free base |
| CAS | 1270084-92-8 |
| MW: | 279.34 D |
ab 52,00 €
(Rac)-SIS3 free base
Artikelnummer: TGM-T12923-100mg
Description: SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-beta1-induced myofibroblast differentiation of fibroblasts. Target: TGF-beta/Smad. Smiles: COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12. References: Jinnin M, et al. Characterization...
| Anwendung: | Smad3 phosphorylation inhibitor |
| CAS | 1009104-85-1 |
| MW: | 453.53 D |
ab 732,00 €
WS-383 free base
Artikelnummer: TGM-T13348-50mg
Description: WS-383 free base is a selective and reversible DCN1-UBC12 interaction inhibitor with an IC50 of 11 nM. Target: Others. Smiles: S(C=1N2C(=NC(SCC3=CC=C(Cl)C=C3)=N2)N=C(C)C1)C=4N(CCN(C)C)N=NN4. References: Wang S, et al. Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5-...
| CAS | 2247543-65-1 |
| MW: | 461.99 D |
ab 1.520,00 €
XL-784 free base
Artikelnummer: TGM-T13357-100mg
Description: XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP) with IC50 values of ~1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. Target: Others. Smiles: S(=O)(=O)(N1C(C(NO)=O)CN(C(OCCOC)=O)CC1)C2=CC(F)=C(OC3=CC=C(Cl)C=C3)C(F)=C2....
| CAS | 1356992-21-6 |
| MW: | 549.93 D |
ab 2.121,00 €
YM-53601 free base
Artikelnummer: TGM-T13371-100mg
Description: YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents. Target: AMPK. Smiles: O(C/C(/F)=C\1/C2CCN(C1)CC2)C=3C=C4C(C=5C(N4)=CC=CC5)=CC3. References: Ugawa T, et al. YM-53601, a novel squalene synthase inhibitor, suppresses...
| CAS | 182959-28-0 |
| MW: | 336.4 D |
ab 1.520,00 €
FR167344 free base
Artikelnummer: TGM-T15347-500mg
Description: FR167344 free base is an orally active, nonpeptide antagonist of the bradykinin receptor B2, exhibiting high-affinity binding (IC50: 65 nM) and showing no binding affinity for the B1 receptor. Target: Others. Smiles:...
| CAS | 215258-13-2 |
| MW: | 673.38 D |
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Itopride free base
Artikelnummer: TGM-T1552L-25mg
Description: Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist. It inhibits lower esophageal sphincter relaxation. It also used to treat functional dyspepsia and gastroesophageal reflux disease. Target: Others. Smiles: COC1=CC=C(C=C1OC)C(=O)NCC1=CC=C(OCCN(C)C)C=C1. References: Mohamed HM. A study...
| Schlagworte: | Itopride hydrochloride, HSR-803, HSR803, HSR 803 |
| Anwendung: | Targets dopamine receptor D2 (DRD2) |
| CAS | 122898-67-3 |
| MW: | 358.43 D |
1.520,00 €
Auramine free base
Artikelnummer: TGM-T20475-500mg
Description: Auramine is an agent of dye. Smiles: N=C(C1=CC=C(C=C1)N(C)C)C2=CC=C(C=C2)N(C)C. References: Wang X, Duan HL, Ma SY, Wang J, Zhan HY, Zhang ZQ. Selective adsorption and separation of illegal cationic dyes from foodstuffs with anionic polyelectrolyte functionalization of metal-organic frameworks. Food...
| Schlagworte: | Auramine, C.I. Solvent Yellow 34 |
| CAS | 492-80-8 |
| MW: | 267.37 D |
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CI-922 free base
Artikelnummer: TGM-T30925-25mg
Description: CI-922 free base is a bio-active chemical. Target: Others. Smiles: O=C(NC1=NN=NN1)C=2OC=3C=4C=C(OC)C=CC4N(C=5C=CC=CC5)C3C2OC
| Schlagworte: | UNII-30275Y0O9C |
| CAS | 89224-56-6 |
| MW: | 404.38 D |
1.520,00 €