Zu "(base)" wurden 1689 Artikel gefunden!
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FOY 251 free base
Artikelnummer: TGM-T11316-500mg
Description: FOY 251 free base acts as a proteinase inhibitor. FOY 251 free base is an anti-proteolytic active metabolite camostate. Target: Others. Smiles: O=C(OC1=CC=C(C=C1)CC(=O)O)C2=CC=C(C=C2)NC(=N)N. References: K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and...
| CAS | 71079-08-8 |
| MW: | 313.31 D |
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FR183998 free base
Artikelnummer: TGM-T11319-10mg
Description: FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger. Target: Na+/Ca2+ Exchanger. Smiles: CN(C)CCNC(=O)c1cc(cc(c1)-c1cc(Cl)sc1Cl)C(=O)NC(N)=N. References: Ohara F, et al. Preischemic and postischemic treatment with a new Na+/H+-exchange inhibitor, FR183998, shows cardioprotective effects in rats...
| CAS | 239440-20-1 |
| MW: | 428.34 D |
ab 103,00 €
FR194738 free base
Artikelnummer: TGM-T11321-10mg
Description: FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. Target: Antifungal. Smiles: CCN(C\C=C\C#CC(C)(C)C)Cc1cccc(OCC(C)(C)OCc2ccsc2)c1. References: Sawada M, et al. Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism...
| CAS | 204067-45-8 |
| MW: | 439.65 D |
ab 83,00 €
FR 167653 free base
Artikelnummer: TGM-T11327L-25mg
Description: FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-alpha and IL-1beta production via specific inhibition of p38 MAPK activity. Target: Others. Smiles:...
| CAS | 158876-65-4 |
| MW: | 427.43 D |
1.520,00 €
JTV-519 free base
Artikelnummer: TGM-T11731-100mg
Description: JTV-519 free base (K201 free base), known for its antiarrhythmic and cardioprotective properties, acts as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and as a partial agonist of ryanodine receptors in striated muscle. Target: FLT. Smiles:...
| Schlagworte: | K201 free base |
| CAS | 145903-06-6 |
| MW: | 424.6 D |
ab 1.520,00 €
KW-8232 free base
Artikelnummer: TGM-T11792-100mg
Description: KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent. Target: Others. Smiles: CN(C)CCn1c(C(=O)N2CCN(CC2)c2ccccc2Cl)c(C(c2ccc(O)cc2)c2ccc(O)cc2)c2ccccc12. References: Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized...
| CAS | 170365-25-0 |
| MW: | 609.16 D |
ab 1.520,00 €
MK-0941 free base
Artikelnummer: TGM-T12056-10mg
Description: MK-0941 free base is an orally active glucokinase activator with potent glucose-lowering activity, making it a potential therapeutic agent for type 2 diabetes. Target: Glucokinase. Smiles: O(C1=CC(C(NC=2C=CN(C)N2)=O)=CC(O[C@H](CO)C)=C1)C=3C=CC(S(CC)(=O)=O)=NC3. References: Eiki J, et al. Pharmacokinetic...
| CAS | 752240-01-0 |
| MW: | 460.5 D |
ab 79,00 €
MT-7716 free base
Artikelnummer: TGM-T12120L-500mg
Description: MT-7716 free base is a selective non-peptide agonist of nociceptin receptor (NOP). It is used for promising potential treatment drugs for alcohol abuse and relapse prevention. Target: Others. Smiles: O=C1N(C2CCN([C@]3(C4=C5C(C3)=CC=CC5=CC=C4)[H])CC2)C=6C(N1CC(NC)=O)=CC=CC6. References: de Guglielmo G,...
| Schlagworte: | W-212393 |
| CAS | 610323-32-5 |
| MW: | 440.54 D |
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BPH-1358 free base
Artikelnummer: TGM-T10586-100mg
Description: BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 µM) and is active against S. aureus in vitro (MIC ~250 ng/mL). Target: Others. Smiles:...
| Schlagworte: | NSC50460 free base |
| CAS | 801985-13-7 |
| MW: | 528.6 D |
ab 1.520,00 €
CS-003 Free base
Artikelnummer: TGM-T10892-50mg
Description: CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases. Target:...
| CAS | 191672-52-3 |
| MW: | 673.65 D |
ab 2.573,00 €
CS-722 Free base
Artikelnummer: TGM-T10893-10mg
Description: CS-722 Free base is a synthetic central muscle relaxant exhibiting muscle relaxant effects and inhibition of spinal reflexes. In hippocampal cultures, CS-722 Free base may suppress spontaneous inhibitory and excitatory post-synaptic currents by inhibiting sodium and calcium currents. Target: Others....
| CAS | 749179-13-3 |
| MW: | 338.79 D |
ab 117,00 €
TT-OAD2 free base
Artikelnummer: TGM-T11406-500mg
Description: TT-OAD2 free base has the potential for diabetes treatment. TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM. Target: Others. Smiles:...
| CAS | 1246826-07-2 |
| MW: | 856.83 D |
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