Sclerostin domain-containing protein 1 (SOSTDC1), recombinant human

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 24-206aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: FKNDATEILY SHVVKPVPAH PSSNSTLNQA RNGGRHFSNT GLDRNTRVQV GCRELRSTKY ISDGQCTSIS PLKELVCAGE CLPLPVLPNW IGGGYGTKYW SRRSSQEWRC VNDKTRTQRI QLQCQDGSTR TYKITVVTAC KCKRYTRQHN ESSHNFESMS PAKPVQHHRE RKRASKSSKH SMS. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling . Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.1 Publication. Reference: n/a. Function: nan