Recombinant Protein (Kit Ligand), scf chicken (cscSCF)

Produced in Yeast. Amino acid sequence: QSSCGNPVTD DVNDIAKLVG NLPNDYLITL KYVPKMDSLP NHCWLHLMVP EFSRSLHNLL QKFSDISDMS DVLSNYSIIN NLTRIINDLM ACLAFDKNKD FIKENGHLYE EDRFIPENFF RLFNSTIEVY KEFADSLDKN DCIMPSTVET PENDSRVAVT KTISFPPVAA SSLRNDSIGS NTSSNSNKEA LGFISSSSLQ (200). Protein function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins. [The UniProt Consortium]