Lymphotoxin-beta (LTB), partial, Pan troglodytes, recombinant

Organism: Pan troglodytes (Chimpanzee). Source: E.coli. Expression Region: 49-244aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: QDQGGLVTET ADPGAQAQQG LGFQKLPEEE PETDLSPGLP AAHLIGAPLK GQGLGWETTK EQAFLTSGTQ FSDAEGLALP QDGLYYLYCL VGYRGRTPPG GGDPQGRSVT LRSSLYRAGG AYGPGTPELL LEGAETVTPV LDPARRQGYG PLWYTSVGFG GLVQLRRGER VYVNISHPDM VDFARGKTFF GAVMVG. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the mbrane anchor for the attachment of the heterotrimeric complex to the cell surface . Reference: Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence.Anzai T., Shiina T., Kimura N., Yanagiya K., Kohara S., Shigenari A., Yamagata T., Kulski J.K., Naruse T.K., Fujimori Y., Fukuzumi Y., Yamazaki M., Tashiro H., Iwamoto C., Umehara Y., Imanishi T., Meyer A., Ikeo K. , Gojobori T., Bahram S., Inoko H.Proc. Natl. Acad. Sci. U.S.A. 100:7708-7713(2003). Function: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface (By similarity).