FGF-10 (human), animal free recombinant

FGF-10 is a growth factor within the FGF family that binds to heparin. Proteins in this family are pivotal during prenatal development, postnatal growth, and tissue regeneration by stimulating cellular proliferation and differentiation. FGF-10 shares close relation to KGF/FGF-7 and is prominently expressed during development, particularly in adult lungs. Its signaling occurs through FGFR 2b. Recombinant Human FGF-10 is a protein weighing 19.3 kDa and comprising 170 amino acid residues. Product Specifications Species Human Published Species Human, Mouse Expression System E.Coli Amino Acid Sequence MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS Molecular Weight 19.3 kDa Class Recombinant Type Protein Purity > 98% by SDS-PAGE gel and HPLC analyses Endotoxin concentration <0.1 EU/µg Activity Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.5-15.0 ng/ml. Form Lyophilized Contains No Preservative CAUTION For Research Use Only. Not for use in diagnostic procedures.Protein function: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. [The UniProt Consortium]