Collagen alpha-1, active (COL15A1), Recombinant, Human

Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. {ECO:0000269, PubMed:10049780}., Restin potently inhibits angiogenesis. {ECO:0000250}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inhibiting the FGF basic-dependent proliferation of HUVEC migration is less than 2.0 ug/mL in the presence of Anti- Human Endostatin Polyclonal Antibody. Sequence: NYEKPALHLA ALNMPFSGDI RADFQCFKQA RAAGLLSTYR AFLSSHLQDL STIVRKAERY SLPIVNLKGQ VLFNNWDSIF SGHGGQFNMH IPIYSFDGRD IMTDPSWPQK VIWHGSSPHG VRLVDNYCEA WRTADTAVTG LASPLSTGKI LDQKAYSCAN RLIVLCIENS FMTDARK, Molecular Weight: 19.8kD, PubMed ID: 8106446, 9651385, 15164053, 8307960, 1279671, 1427836, 15698950, 10049780, 10791950, 22171320, Gene Name: COL15A1, Swiss Prot: P39059, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.