CCL20 (mouse):Fc (mouse) (rec.)

CCL20 (mouse):Fc (mouse) (rec.)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
CHI-MF-110CCL20-C050 50 µg - -

3 - 9 Werktage*

341,00 €
 
Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver... mehr
Produktinformationen "CCL20 (mouse):Fc (mouse) (rec.)"
Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products. MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Deregulation of miRNAs and chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis and the regulation of CCL20 expression by miR-21 might be a regulatory mechanism involved in progression of colorectal cancer (CRC).
Schlagworte: Larc, Ccl20, MIP-3-alpha, CC chemokine ST38, CC chemokine LARC, C-C motif chemokine 20, Beta-chemokine exodus-1, Small-inducible cytokine A20, Macrophage inflammatory protein 3 alpha, Liver and activation-regulated chemokine, Chemokine (C-C motif) ligand
Hersteller: Chimerigen Laboratories
Hersteller-Nr: MF-110CCL20

Eigenschaften

Anwendung: Bioassays
Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Mouse
MW: ~38 kD
Reinheit: >95%
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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