Biotinylated Human IL-18 Protein (Primary Amine Labeling)

Recombinant Biotinylated Human IL-18 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Tyr37-Asp193. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-gamma production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-gamma production in response to IL-18 stimulation.