BAFF (TNFSF13B), mouse recombinant (rmoBAFF)

Produced in Yeast. Amino acid sequence: AFQGPEETEQ DVDLSAPPAP CLPGCRHSQH DDNGMNLRNI IQDCLQLIAD SDTPTIRKGT YTFVPWLLSF KRGNALEEKE NKIVVRQTGY FFIYSQVLYT DPIFAMGHVI QRKKVHVFGD ELSLVTLFRC IQNMPKTLPN NSCYSAGIAR LEEGDEIQLA IPRENAQISR NGDDTFFGAL KLL (183). Protein function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B- cells and the B-cell response. [The UniProt Consortium]