TGF beta1, Recombinant, Human (TGF beta 1, TGFb1, Camurati Engelmann Disease, CED, Diaphyseal Dyspla

Transforming growth factor beta 1(TGF-beta1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. Many cells synthesize TGFb1 and almost all of them have specific receptors for it. It positively and negatively regulates many other growth factors. Also, TGF-beta1 plays an important role in bone remodeling, controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Recombinant TGF-beta1 protein , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human TGF beta1, aa279-390, expressed in E. coli, AA Sequence: MALDTNYCFS STEKNCCVRQ LYIDFRKDLG WKWIHEPKGY HANFCLGPCP YIWSLDTQYS KVLALYNQHN PGASAAPCCV PQALEPLPIV YYVGRKPKVE QLSNMIVRSC KCS, Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.