Human ADCYAP1R1 N-ECD, recombinant (C-6His)

Recombinant Human Pituitary adenylate cyclase-activating polypeptide type I receptor is produced by our Mammalian expression system and the target gene encoding Met21-Ala155 is expressed with a 6His tag at C-terminus. Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. [The UniProt Consortium]