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Zu "K04587" wurden 26 Artikel gefunden!
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Artikelnummer: GSC-M00203
Recombinant CHO-K1 cells stably overexpress human pituitary adenylate cyclase-activating polypeptide type I receptor (PAC1) on the surface and contain high levels of G protein Galphaq and Galphas to couple with the receptor in downstream signaling pathways.
| Schlagworte: | ADCYAP1R1, Pituitary adenylate cyclase-activating polypeptide type I receptor |
11.424,00 €
Artikelnummer: Cay42131-10
A PAC1 receptor antagonist, selectively inhibits PACAP-induced CREB phosphorylation in CHO cells expressing the PAC1 receptor over CHO cells expressing VPAC1 or VPAC2 at 10 nM, inhibits PACAP-induced cAMP accumulation in CHO cells expressing the PAC1 receptor (IC50 = 2 nM), intrathecal administration reduces...
| Schlagworte: | 2-amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]-pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione |
| Anwendung: | PAC1 receptor antagonist |
| CAS | 878437-15-1 |
| MW: | 342.4 D |
ab 58,00 €
Artikelnummer: ARG56232.100
Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis...
| Schlagworte: | Anti-PACAP-R1, Anti-PACAP-R-1, Anti-ADCYAP1R1, Anti-PACAP type I receptor, Anti-Pituitary adenylate cyclase-activating... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Artikelnummer: G-HUFI01466.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: ATA-HPA030739.100
Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis...
| Schlagworte: | Anti-PACAP-R1, Anti-ADCYAP1R1, Anti-PACAP-R-1, Anti-PACAP type I receptor, Anti-Pituitary adenylate cyclase-activating... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Artikelnummer: ATA-HPA049877.100
Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis...
| Schlagworte: | Anti-PACAP-R1, Anti-ADCYAP1R1, Anti-PACAP-R-1, Anti-PACAP type I receptor, Anti-Pituitary adenylate cyclase-activating... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Artikelnummer: CSB-PA207627.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ADCYAP1R1. Antigen Species: Human
| Schlagworte: | Anti-PACAP-R1, Anti-PACAP-R-1, Anti-ADCYAP1R1, Anti-PACAP type I receptor, Anti-Pituitary adenylate cyclase-activating... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: TGM-TMPY-02648-50ug
Description: Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and...
| Schlagworte: | PACAPRI, PAC1R, adenylate cyclase activating polypeptide 1 (pituitary) receptor type I, PACAPR, PAC1 |
| MW: | 42 kD |
658,00 €
Artikelnummer: Cay41333-5
NN1177 is a dual peptide agonist of the glucagon receptor (GCGR) and glucagon-like peptide 1 receptor (GLP-1R). It induces cAMP production in BHK-21 cells expressing human GCGR or GLP-1R (EC50s = 1.83 and 0.92 pM, respectively). In vivo, NN1177 (3-5 nmol/kg) reduces body weight and cumulative food intake in a mouse...
| Anwendung: | Dual peptide GCGR / GLP-1R agonist |
| MW: | 4570.1 D |
ab 147,00 €
Artikelnummer: NOV-C42K.100ug
Recombinant Human ADCYAP1R1 is produced by our Mammalian expression system and the target gene encoding Met21-Ser417 is expressed with a 6His, Flag tag at C-terminus. Some mutations are introduced to stabilize the Human ADCYAP1R1 protein. VLPs are self-assembled from viral envelope/capsid protein and can display...
| Schlagworte: | PACAP-R1, ADCYAP1R1, PACAP-R-1, PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 48.2 kD |
ab 780,00 €
Artikelnummer: NOV-C44W.100ug
Recombinant Human Pituitary adenylate cyclase-activating polypeptide type I receptor is produced by our Mammalian expression system and the target gene encoding Met21-Ser416 is expressed with a 6His, Flag tag at C-terminus. VLPs are self-assembled from viral envelope/capsid protein and can display conformationally...
| Schlagworte: | PACAP-R1, ADCYAP1R1, PACAP-R-1, PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 48.2 kD |
ab 780,00 €
Artikelnummer: G-HDFP1163.10
Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis...
| Schlagworte: | PACAP-R1, PACAP-R-1, ADCYAP1R1, PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.605,00 €