DRD4 PrEST Antigen

PrEST Antigen DRD4, Gene description: dopamine receptor D4, Antigen sequence: YSEVQGGAWLLSPRLCDALM, Storage: Upon delivery store at -20°C. Avoid repeated freeze/thaw cycles. Protein function: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells. [The UniProt Consortium] Mouse gene identity: 90% Rat gene identity: 90%