PM20D1 (Vector pUC, Accession No. BC063477)

Length: 1509 Sequence: atggctcagc ggtgcgtttg cgtgctggcc ctggtggcta tgctgctcct agttttccct accgtctcca gatcgatggg cccgaggagc ggggagcatc aaagggcgtc gcgaatccct tctcagttca gcaaagagga acgcgtcgcg atgaaagagg cgctgaaagg tgccatccag attccaacag tgacttttag ctctgagaag tccaatacta cagccctggc tgagttcgga aaatacattc ataaagtctt tcctacagtg gtcagcacca gctttatcca gcatgaagtc gtggaagagt atagccacct gttcactatc caaggctcgg accccagctt gcagccctac ctgctgatgg ctcactttga tgtggtgcct gcccctgaag aaggctggga ggtgccccca ttctctgggt tggagcgtga tggcgtcatc tatggttggg gcacactgga cgacaagaac tctgtgatgg cattactgca ggccttggag ctcctgctga tcaggaagta catcccccga agatctttct tcatttctct gggccatgat gaggagtcat cagggacagg ggctcagagg atctcagccc tgctacagtc aaggggcgtc cagctagcct tcattgtgga cgaggggggc ttcatcttgg atgatttcat tcctaacttc aagaagccca tcgccttgat tgcagtctca gagaagggtt ccatgaacct catgctgcaa gtaaacatga cttcaggcca ctcttcagct cctccaaagg agacaagcat tggcatcctt gcagctgctg tcagccgatt ggagcagaca ccaatgccta tcatatttgg aagcgggaca gtggtgactg tattgcagca actggcaaat gagtttccct tccctgtcaa tataatcctg agcaacccat ggctatttga accacttata agcaggttta tggagagaaa tcccttaacc aatgcaataa tcaggaccac cacggcactc accatattca aagcaggggt caagttcaat gtcatccccc cagtggccca ggccacagtc aacttccgga ttcaccctgg acagacagtc caagaggtcc tagaactcac gaagaacatt gtggctgata acagagtcca gttccatgtg ttgagtgcct ttgaccccct ccccgtcagc ccttctgatg acaaggcctt gggctaccag ctgctccgcc agaccgtaca gtccgtcttc ccggaagtca atattactgc cccagttact tctattggca acacagacag ccgattcttt acaaacctca ccactggcat ctacaggttc taccccatct acatacagcc tgaagacttc aaacgcatcc atggagtcaa cgagaaaatc tcagtccaag cctatgagac ccaagtgaaa ttcatctttg agttgattca gaatgctgac acagaccagg agccagtttc tcacctgcac Protein function: Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase (PubMed:27374330). It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction (PubMed:27374330). Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1- independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles. [The UniProt Consortium]