IFI6 (Vector pUC, Accession No. BC011601)

Length: 393 Sequence: atgcggcaga aggcggtatc gcttttcttg tgctacctgc tgctcttcac ttgcagtggg gtggaggcag gtaagaaaaa gtgctcggag agctcggaca gcggctccgg gttctggaag gccctgacct tcatggccgt cggaggagga ctcgcagtcg ccgggctgcc cgcgctgggc ttcaccggcg ccggcatcgc ggccaactcg gtggctgcct cgctgatgag ctggtctgcg atcctgaatg ggggcggcgt gcccgccggg gggctagtgg ccacgctgca gagcctcggg gctggtggca gcagcgtcgt cataggtaat attggtgccc tgatgggcta cgccacccac aagtatctcg atagtgagga ggatgaggag Protein function: Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (PubMed:15685448, PubMed:17823654, PubMed:26244642). However, it has also been shown to have a pro-apoptotic activity (PubMed:27673746). Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571). [The UniProt Consortium]