U-44069

U-44069 is a stable analog of the endoperoxide PGH2 (Cay-17020) and a TP receptor agonist. It stimulates shape change in human platelets without a measurable increase in Ca2+ with an EC50 value of 1.8 nM. U-44069 has an EC50 value of 3 µM and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively.Formal Name: 9,11-dideoxy-9alpha,11alpha-epoxymethano-prosta-5Z,13E-dien-1-oic acid. CAS Number: 56985-32-1. Synonyms: 9,11-dideoxy-9alpha,11alpha-epoxymethano PGF2alpha, 9,11-dideoxy-9alpha,11alpha-epoxymethano Prostaglandin F2alpha, 9,11-epoxymethano Prostaglandin H2. Molecular Formula: C21H34O4. Formula Weight: 350.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >100 mg/ml (from U-46619), DMSO: >100 mg/ml (from U-46619), Ethanol: >100mg/ml (from U-46619), PBS pH 7.2: >2 mg/ml (from U-46619). SMILES: CCCCC[C@H](O)/C=C/[C@H]1C(CO2)CC2[C@@H]1C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16?,17-,18-,19+,20?/m0/s1. InChi Key: DJKDIKIDYDXHDD-REGKDVDGSA-N.