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Zu "K04264" wurden 26 Artikel gefunden!
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Artikelnummer: Cay14059-5
The lipid mediator thromboxane A2 (TXA2) plays a key role in platelet aggregation and vascular and bronchial smooth muscle constriction. The actions of TXA2 are mediated by its specific G protein coupled-receptor, referred to as the TXA2 receptor or TP. S18886 is an orally active, long-acting antagonist of the TP...
Schlagworte: | Terutroban, Triplion, (6R)-6-[[(4-chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-naphthalenepropanoic |
Anwendung: | TXA2 receptor antagonist |
CAS | 165538-40-9 |
MW: | 407.9 D |
ab 98,00 €
Artikelnummer: Cay9002014-10
Seratrodast is a potent antagonist of the thromboxane A2 (TXA2) receptor (TP), blocking specific binding of U-46619 (Cay-16450) to guinea pig platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 (Cay-16440) with an IC50 value of 350 nM. It is metabolized, in liver microsomes, by...
Schlagworte: | A-73001, AA2414, ABT-001, zeta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-benzeneheptanoic acid |
Anwendung: | Thromboxane A2 (TXA2) receptor antagonist |
CAS | 112665-43-7 |
MW: | 354.4 D |
ab 60,00 €
Artikelnummer: ARG56548.250
Protein function: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense...
Schlagworte: | Anti-TXA2-R, Anti-TBXA2R, Anti-Prostanoid TP receptor, Anti-Thromboxane A2 receptor |
Anwendung: | FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, african green monkey |
656,00 €
Artikelnummer: LKT-S1968.25
A thromboxane receptor antagonist used primarily in the treatment of asthma.
Anwendung: | Thromboxane A2 (TXA2) receptor antagonist |
CAS | 112665-43-7 |
MW: | 354,44 D |
ab 223,00 €
Artikelnummer: Cay14061-5
Daltroban is a thromboxane receptor (TP) antagonist. It inhibits aggregation of isolated human platelets induced by the TP agonist U-46619 (Item no. 16450, IC50 = 77 nM). Daltroban increases mean pulmonary arterial pressure (MPAP), mean arterial pressure (MAP), and hematocrit levels in anesthetized rats (ED50s = 20,...
Schlagworte: | BM 13505, SKF 96148, 4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]-benzeneacetic acid |
Anwendung: | Thromboxane A2 (TXA2) receptor antagonist |
CAS | 79094-20-5 |
MW: | 353.8 D |
ab 58,00 €
Artikelnummer: ARG56514.250
Protein function: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense...
Schlagworte: | Anti-TXA2-R, Anti-TBXA2R, Anti-Prostanoid TP receptor, Anti-Thromboxane A2 receptor |
Anwendung: | ICC, IF, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, african green monkey |
656,00 €
Artikelnummer: LKT-R0248.10
A thromboxane receptor antagonist, a CRTH2 antagonist. It is indicated for the treatment of coronary artery disease. It has also been used for the treatment of asthma. Also prostaglandin D2 receptor antagonist.
Anwendung: | TXA2 receptor antagonist |
CAS | 116649-85-5 |
MW: | 416,47 D |
ab 202,00 €
Artikelnummer: Cay10012559-1
Thromboxane A2 (TXA2) is a potent vasoconstrictor and activator of platelet aggregation. The short half-life of TXA2 ensures local action whether generated by vascular endothelial cells or by platelets and confers physiologically beneficial or deleterious effects under inflammatory situations. TXA2 elicits its...
Schlagworte: | Anti-TBXA2R, Anti-TXA2-R, Anti-TXA2-R, Anti-Prostanoid TP receptor, Anti-Prostanoid TP receptor, Anti-Thromboxane A2... |
Anwendung: | FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, murine, rat, Cos-7 |
472,00 €
Artikelnummer: Cay10135-1
ICI 192605 is a potent antagonist of the thromboxane A2 receptor (TP) that blocks contraction of isolated guinea pig trachea induced by U-46619 (Cay-16450, Kd = 0.398 nM). It is used to study the role of TP signaling in tissues and animals.Formal Name:...
Schlagworte: | (4Z)-rel-6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic acid |
Anwendung: | Thromboxane A2 receptor antagonist |
CAS | 117621-64-4 |
MW: | 402.9 D |
ab 43,00 €
Artikelnummer: Cay21690-10
Picotamide is an antiplatelet drug that inhibits both thromboxane A2 (TXA2) receptors (Kd = 325 nM) and TXA2 synthase. It significantly inhibits basal and lipopolysaccharide-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM. Formulations containing picotamide have potential applications in...
Schlagworte: | 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide |
Anwendung: | TXA2 receptor antagonist / TXA2 synthase inhibitor |
CAS | 32828-81-2 |
MW: | 376.4 D |
ab 84,00 €
Artikelnummer: E-AB-17491.120
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene....
Schlagworte: | Anti-TBXA2R, Anti-TXA2-R, Anti-Prostanoid TP receptor, Anti-Thromboxane A2 receptor, TBXA2R Polyclonal Antibody |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €
Artikelnummer: E-AB-17492.120
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene....
Schlagworte: | Anti-TBXA2R, Anti-TXA2-R, Anti-Prostanoid TP receptor, Anti-Thromboxane A2 receptor, TBXA2R Polyclonal Antibody |
Anwendung: | WB, IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €