PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)

PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007764-100 100 µg -

6 - 10 Werktage*

81,00 €
Cay10007764-500 500 µg -

6 - 10 Werktage*

347,00 €
Cay10007764-1 1 mg -

6 - 10 Werktage*

612,00 €
 
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane... mehr
Produktinformationen "PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)"
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The short fatty acid chains of this analog give it different physical properties including high solubility in aqueous media compared to naturally occurring PtdIns-(3,4,5)-P3. PtdIns are phosphorylated to mono- (PtdIns-P, PIP), di- (PtdIns-P2, PIP2), and triphosphates (PtdIns-P3, PIP3). Phosphorylation of PtdIns-(4,5)-P2 by phosphoinositide (PI)-3-kinase initiates an intricate signalling cascade at the fore front of scientific research.Formal Name: 1-(1,2-dioctanoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt. Synonyms: DOPI-3,4,5-P3, Phosphatidylinositol-3,4,5-trisphosphate, PIP3[3',4',5'](8:0/8:0), PI(3,4,5)P3 (8:0/8:0). Molecular Formula: C25H46O22P4 . 4Na. Formula Weight: 914.5. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. SMILES: O=C(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O[P+]([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O])(O)=O)[C@H]1O)([O-])=O)OC(CCCCCCC)=O)CCCCCCC.[Na+].[Na].[Na+].[Na]. InChi Code: InChI=1S/C25H50O22P4.4Na/c1-3-5-7-9-11-13-18(26)41-15-17(43-19(27)14-12-10-8-6-4-2)16-42-51(39,40)47-22-20(28)23(44-48(30,31)32)25(46-50(36,37)38)24(21(22)29)45-49(33,34)35,,,,/h17,20-25,28-29H,3-16H2,1-2H3,(H,39,40)(H2,30,31,32)(H2,33,34,35)(H2,36,3. InChi Key: HKEJKRRMHQTDJY-JQCOAGCCSA-J. Side Chain Carbon Sum: 16:0.
Schlagworte: DOPI-3,4,5-P3, Phosphatidylinositol-3,4,5-trisphosphate, 1-(1,2-dioctanoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt
Hersteller: Cayman Chemical
Hersteller-Nr: 10007764

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 914.5 D
Formel: C25H46O22P4 . 4Na
Reinheit: >98%
Format: Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
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