Oleoyl Ethanolamide Phosphate

Oleoyl ethanolamide phosphate (OEA-P) is a lysophosphatidic acid (LPA) mimetic, LPA receptor agonist, and phosphate ester of oleoyl ethanolamide (OEA, Cay-90265). It selectively increases [35S]GTPgammaS binding to HEK293T cell membranes expressing LPA1 and LPA2 over LPA3 receptors. OEA-P induces calcium mobilization and inhibits forskolin-induced cAMP accumulation in MDA-MB-231 cells (EC50s = 1.2 and 101 nM, respectively).Formal Name: N-[2-(phosphonooxy)ethyl]-9Z-octadecenamide. CAS Number: 24435-25-4. Synonyms: NAEPA, N-oleoyl ethanolamide phosphoric acid, OEA-P. Molecular Formula: C20H40NO5P. Formula Weight: 405.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. SMILES: OP(OCCNC(CCCCCCC/C=C\CCCCCCCC)=O)(O)=O. InChi Code: InChI=1S/C20H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)21-18-19-26-27(23,24)25/h9-10H,2-8,11-19H2,1H3,(H,21,22)(H2,23,24,25)/b10-9-. InChi Key: BCSUWOZFWWBYSX-KTKRTIGZSA-N.