Zu "K04289" wurden 49 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NEU
Human LPAR1 (Lysophosphatidic Acid Receptor 1)...
Artikelnummer: ELK-ELK3504MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LPAR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LPAR1. Next,...
| Schlagworte: | LPAR1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor Edg-2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
H2L 5765834
Artikelnummer: Cay45940-1
H2L 5765834 is an antagonist of lysophosphatidic acid receptor 1 (LPA1), LPA3, and LPA5 (IC50s = 94, 752, and 463 nM, respectively). It is selective for these receptors over LPA2 and LPA4. H2L 5765834 (50 µM) reverses increases in viability induced by overexpression of the gene encoding autotaxin, also known as...
| Schlagworte: | 2,3-dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid |
| Anwendung: | LPAR1 / LPAR3 / LPAR5 antagonist |
| CAS | 420841-84-5 |
| MW: | 404.33 D |
ab 83,00 €
Ki16425
Artikelnummer: Cay10012659-10
Lysophosphatidic acid (LPA) is a bioactive lipid mediator that signals through five distinct G protein-coupled receptors (LPA1-5). Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors, respectively, as...
| Schlagworte: | 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazoly]phenyl]methyl]thio]-propanoic acid |
| Anwendung: | LPA receptor antagonist |
| CAS | 355025-24-0 |
| MW: | 475 D |
ab 58,00 €
Anti-LPA1
Artikelnummer: Cay10005280-1
LPA1 (also known as EDG-2) is one of four known LPA receptors (LPA1-4). LPA1-3 are part a family of G protein-coupled receptors that share identity to the sphingosine-1-phosphate receptors (S1P1-5). LPA1 couples with three types of G proteins, Gi/o, Gq, and G12/13 to induce a range of cellular responses including...
| Schlagworte: | Anti-EDG2, Anti-LPAR1, Anti-LPA-1, Anti-LPA-1, Anti-LPA receptor 1, Anti-LPA receptor 1, Anti-Lysophosphatidic acid... |
| Anwendung: | ICC, IF, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-PC
Artikelnummer: Cay25595-5
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Cay-10011298) and docosahexaenoic acid (DHA, Cay-90310) at the sn-1 and sn-2 positions, respectively. It has been used in the study of lipid membrane organization and dynamics. The levels of...
| Schlagworte: | 18:0/22:6 PC, 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-Phosphatidylcholine,... |
| Anwendung: | Lysophospholipid |
| CAS | 59403-52-0 |
| MW: | 834.2 D |
ab 114,00 €
AM966
Artikelnummer: Cay22048-1
AM966 is an orally bioavailable, potent, and selective antagonist of the lysophosphatidic acid receptor 1 (LPA1) that has an IC50 value of 17 nM in a calcium assay using CHO cells transfected with the human LPA1 receptor. It is selective for LPA1 over the LPA2, LPA3, LPA4, and LPA5 receptors (IC50s = 1,700, 1,600,...
| Schlagworte: | 4'-[4-[[[(1R)-1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]-[1,1'-biphenyl]-4-acetic acid |
| Anwendung: | LPAR1 antagonist |
| CAS | 1228690-19-4 |
| MW: | 490.9 D |
ab 73,00 €
BMS 986278
Artikelnummer: Cay43597-10
BMS 986278 is an antagonist of lysophosphatidic acid receptor 1 (LPA1, Kb = 0. µM). It is selective for LPA1 over a panel of 44 receptors, ion channels, and enzymes when used at concentrations ranging from 30 to 150 µM, including the bile salt export pump (BSEP), multidrug resistance protein 3 (MDR3), multidrug...
| Schlagworte: | Admilparant,... |
| Anwendung: | LPA1 antagonist |
| CAS | 2170126-74-4 |
| MW: | 445.52 D |
ab 269,00 €
Lipid-based Drug Delivery-Tools
1-Oleoyl-2-hydroxy-sn-glycero-3-PE
Artikelnummer: Cay25596-5
1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid...
| Schlagworte: | 18:1 LPE, 18:1 Lyso-PE, 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine,... |
| Anwendung: | Lysophospholipid |
| CAS | 89576-29-4 |
| MW: | 479.6 D |
ab 76,00 €
BMS 986020
Artikelnummer: Cay22049-1
BMS 986020 is an antagonist of lysophosphatidic acid receptor 1 (LPA1, Kb = 0.0067 µM). It is selective for LPA1 over LPA3 in CHO cells expressing the human receptors (IC50s = 0.3 and >1 µM, respectively). BMS 986020 also inhibits organic anion transporting polypeptide 1B1 (OATP1B1), OATP1B3, the bile salt export...
| Schlagworte: | 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-cyclopropanecarboxylic acid |
| Anwendung: | LPAR1 antagonist |
| CAS | 1257213-50-5 |
| MW: | 482.5 D |
ab 51,00 €
AM095
Artikelnummer: Cay22141-5
AM095 is an orally bioavailable antagonist of lysophosphatidic acid receptor 1 (LPA1) with IC50 values of 25 and 23 nM in CHO cells expressing human or mouse receptors, respectively. It is selective for LPA1 over LPA2, LPA3, LPA4, and LPA5 (IC50s = >10,000 nM for human LPA2-5). It inhibits chemotaxis of CHO cells...
| Schlagworte: | 4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]-[1,1'-biphenyl]-4-acetic acid |
| Anwendung: | LPA1 antagonist |
| CAS | 1228690-36-5 |
| MW: | 456.5 D |
ab 126,00 €
1-Stearoyl-2-hydroxy-sn-glycero-3-PE
Artikelnummer: Cay25593-10
1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid. It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 (Cay-22141).Formal Name:...
| Schlagworte: | 18:0 LPE, 18:0 Lyso PE, 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine, 1-Stearoyl LPE, 1-Stearoyl lyso-PE,... |
| Anwendung: | Lysophospholipid |
| CAS | 69747-55-3 |
| MW: | 481.6 D |
ab 151,00 €
Human LPAR1 / LPA1 / EDG2 ELISA Kit
Artikelnummer: G-HUFI02151.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €