N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (chloride)

N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium (DOTMA) is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.Formal Name: N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecen-1-yloxy]-1-propanaminium, monochloride. CAS Number: 104162-48-3. Synonyms: DOTMA. Molecular Formula: C42H84NO2 . Cl. Formula Weight: 670.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 5 mg/ml, DMSO: 0.5 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 225 nm. SMILES: CCCCCCCC/C=C\CCCCCCCCOC(C[N+](C)(C)C)COCCCCCCCC/C=C\CCCCCCCC.[Cl-]. InChi Code: InChI=1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2,/h20-23,42H,6-19,24-41H2,1-5H3,1H/q+1,/p-1/b22-20-,23-21-,. InChi Key: LDGWQMRUWMSZIU-LQDDAWAPSA-M.